Side Effects

Does Ozempic Cause Tooth Decay & How Can You Keep Your Teeth Safe?

James Madison, GLP-1 Expert

James Madison, GLP-1 Expert

Aug 28, 2025

Aug 28, 2025

woman in pain - Does Ozempic Cause Tooth Decay
woman in pain - Does Ozempic Cause Tooth Decay

Over the past few years, Ozempic has evolved from a diabetes treatment to a cultural phenomenon. Alongside stories of dramatic weight loss, a flood of side effects has made headlines, everything from Ozempic hair to Ozempic face to relentless gastrointestinal complaints. This article cuts through the noise by asking a direct question: Does Ozempic cause tooth decay? Additionally, What to Expect With Semaglutide? You’ll see what the science and dentists actually say, why side effects like dry mouth matter, and which simple oral care steps make the most significant difference.

To support these steps, MeAgain’s GLP-1 app helps you track medication, flag early signs of dry mouth, and set reminders for hydration and dental checkups, so you can focus on the benefits of Ozempic while protecting your teeth for the long run.

Table of Contents

Does Ozempic Cause Tooth Decay? The Short Answer Clinicians Offer

Does Ozempic Cause Tooth Decay

Current evidence does not indicate that semaglutide or Ozempic directly dissolve enamel or cause cavities on their own. Researchers and dental professionals view the reports as indirect effects associated with the side effects of these medications. Catrise Austin, DDS, puts it plainly: “While not officially labeled as a clinical diagnosis, ‘Ozempic teeth’ is becoming a catch-all phrase describing the sudden onset of dental decay, sensitivity, and even tooth loss in patients on these medications,” she told Healthline. Clinically, the medication is not listed as a tooth-destroying agent, yet accumulating patient reports and plausible biological mechanisms make the link worth attention.

Which GLP-1 Drugs are Involved, and Why Does the Pattern Appear Across the Class

Patients taking semaglutide products, such as Ozempic and Wegovy, commonly report oral changes; semaglutide is not the only agent associated with these complaints. Other GLP-1 and related drugs include: 

  • Tirzepatide, sold under the brands Mounjaro and Zepbound

  • Liraglutide, available as Saxenda and Victoza

  • Dulaglutide, known as Trulicity

  • Exenatide, marketed as Byetta and Bydureon BCise

Similar side effects can appear across this class because they share digestive and appetite-altering actions that affect: 

  • Saliva

  • Reflux

  • Nausea

  • Eating patterns

How Reduced Saliva Flow Raises Decay Risk And Damages Enamel

Saliva defends the mouth in several ways. It buffers acids, supplies minerals that help: 

  • Eemineralize early enamel loss

  • Washes away food particles and sugars

  • Supports a balanced oral microbiome

When salivary flow decreases, plaque builds up more quickly, and acid from bacteria remains in contact with the enamel for more extended periods. Austin described this clearly: “Reduced salivary flow is one of the most common complaints I hear from patients on GLP-1 medications,” she said. Less saliva means weaker neutralization of acids and reduced remineralization, which increases the risk of cavities and gum inflammation.

Why Nausea, Vomiting, and Acid Reflux Can Cause Enamel Erosion

Frequent reflux or vomiting exposes teeth to stomach acid. That acid softens and dissolves enamel, increasing sensitivity and structural breakdown. Austin noted clinical trial side effect rates reported to regulators: clinical data reported by the Food and Drug Administration show that nausea occurs in 16% to 20% of patients who use Ozempic. 5 to 9 percent have vomiting. As Austin explains, “Repeated exposure to stomach acid can erode tooth enamel and increase sensitivity.” Even intermittent episodes of reflux or vomiting raise the risk when they repeat over weeks or months.

How Appetite Suppression and Eating Pattern Changes Affect Dental Health

These medications slow gastric emptying and suppress hunger. For some people, this leads to: 

  • Skipped meals

  • Smaller portions

  • Nutrient gaps

  • Add snack choices

Austin flagged the nutrition angle: “Some patients experience appetite suppression to the point of nutrient deficiency, which can affect gum health and healing.” Lower intake of calcium, vitamin D, vitamin C, and B vitamins can impair gum tissue resilience and wound healing. Chewing less also reduces saliva stimulation, which can worsen dry mouth. In some cases, people choose softer, carbohydrate-rich snacks because of nausea, which can increase cavity risk if oral hygiene slips.

What Patients and Dentists are Reporting When They Say Ozempic Teeth

Reports labeled Ozempic teeth vary but often include: 

  • Dry mouth

  • Enamel erosion

  • Increased sensitivity

  • Inflamed gums

  • Bad breath

  • Cracked or loose teeth

  • Tooth loss

Austin observed that online and clinic anecdotes have grown louder: “Though anecdotal, these stories have gained traction as more users share alarming dental side effects online and in media reports,” she said. Patients commonly describe changes soon after starting therapy, such as persistent bad breath or a sticky feeling from low saliva.

Why Does Bad Breath Appear, and How Does It Link To Reflux And Slowed Digestion

Bad breath may come from altered digestion and slower stomach emptying. Sluggish digestion raises the chance of acid reflux and regurgitation of stomach contents into the mouth. Austin outlined the mechanism and the smell: delayed stomach emptying can push acids back up into the esophagus and sometimes the mouth, producing a sour or metallic breath. 

Reflux can also irritate soft tissues and expose enamel to acid, thereby increasing oral risk and producing persistent halitosis.

Practical Steps A Patient Can Take Right Now To Protect Teeth While On GLP-1 Therapy

  • Ask your dentist for a check-up soon after starting the medication and report any new symptoms, such as dry mouth, sensitivity, or reflux. 

  • Stay well-hydrated and sip water frequently to keep your mouth moist. 

  • Chew sugar-free gum that contains xylitol to stimulate saliva when tolerated. 

  • Use fluoride toothpaste and consider professional fluoride varnish or prescription fluoride rinses to strengthen enamel. 

  • If vomiting occurs, rinse with plain water or a baking soda solution, then wait at least 30 minutes before brushing to avoid brushing softened enamel. 

  • Control reflux with your clinician’s help; reducing acid exposure helps protect your teeth. 

  • Address nutritional gaps with a clinician-guided plan that focuses on calcium, vitamin D, vitamin C, and B vitamins to support optimal gum health. 

  • Ask about saliva substitutes, prescription saliva stimulants, or topical agents if dry mouth persists. 

  • Maintain regular dental cleanings and monitor for early signs of decay, allowing for conservative interventions.

Questions To Ask Your Clinician and Dentist About Medications and Oral Risk

  • Have you noticed an increase in dry mouth or mouth pain since starting treatment? 

  • Are there signs of early enamel erosion or rapid new cavities? 

  • Can we optimize my nutrition to support gum healing? 

  • Should I add a fluoride rinse or receive professional fluoride treatment? 

  • How can we manage nausea and reflux so they do not harm my teeth? 

These questions guide focused action and let your care team coordinate: 

  • Medication

  • Nutrition

  • Oral health measures

Related Reading

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Why Does Mounjaro Cause Diarrhea
Why Does Mounjaro Cause Burping
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How to Protect Your Teeth When Using Ozempic

How to Protect Your Teeth When Using Ozempic

Daily Mouth Care That Stops Decay Before It Starts

Brush twice a day for two minutes using a soft brush and fluoride toothpaste. Use gentle circular strokes along the gumline and on chewing surfaces. Floss once a day to remove plaque between teeth and under the gumline. Finish with a fluoride rinse if your dentist recommends one or if you are at higher risk for cavities. How long since your last professional fluoride treatment or prescription-strength toothpaste?

Keep Your Mouth Moist: Hydration and Saliva Support

Dry mouth increases the risk of enamel erosion, bad breath, and cavities because saliva neutralizes acid and helps wash away food particles. Sip plain water frequently throughout the day, and consider keeping a glass at your bedside to help alleviate nighttime dryness if it's an issue. Try an over-the-counter saliva-promoting rinse or a saliva substitute; look for products labeled for dry mouth or containing xylitol. Chew sugar-free gum with xylitol after meals to stimulate saliva production and reduce acid attack on enamel.

Diet Choices That Protect Your Teeth While Losing Weight

Avoid frequent consumption of sugary snacks and acidic drinks, as they can strip enamel. When you skip meals due to a drop in appetite from GLP-1 medication, make each meal nutrient-dense by including calcium-rich foods and vitamin D sources to support bone and tooth health. For steady weight loss, aim for a moderate calorie deficit of around 300 to 500 calories per day rather than extreme restriction. Which snacks do you reach for when hunger is low? Swap sugary or sticky options for: 

  • Cheese

  • Nuts

  • Fresh fruit in moderation

Daily Habits That Reduce Risk of Enamel Erosion and Sensitivity

Rinse your mouth with water after acidic foods or drinks. Avoid brushing immediately after vomiting or acid reflux; the enamel is softened, and you can abrade it. Instead, mix about a half-teaspoon of baking soda in 8 ounces of water and rinse to neutralize stomach acid. Then, wait 30 to 60 minutes before brushing your teeth. Use toothpaste formulated for sensitivity if sensitivity develops. Replace your brush every three months, or sooner if the bristles become frayed.

Products and Tools Worth Using

Choose a soft toothbrush, fluoride toothpaste, interdental cleaners or floss, and a fluoride mouthwash if advised by your dentist. Consider an alcohol-free saliva-enhancing rinse and sugar-free gum with xylitol. If you exhibit enamel erosion or rapid tooth decay, your dentist may recommend a high-fluoride toothpaste or apply a professional fluoride varnish to help protect your teeth. Ask about topical treatments and sealants that protect vulnerable surfaces during active weight loss.

Avoiding Things That Make Dry Mouth and Decay Worse

Alcohol, tobacco, and caffeine can all worsen dry mouth and promote cavities by reducing saliva flow. If you smoke or vape, talk with your care team about strategies to quit. Reduce your intake of energy drinks and soda, which can cause the mouth to become acidic. Choose water or plain unsweetened tea instead to keep saliva working and acids in check.

What to Do If You Have Nausea or Frequent Vomiting

If nausea or vomiting becomes regular, contact the clinician managing your GLP-1 medication. They may adjust the dose or add medication to reduce nausea and protect your stomach. For your teeth, rinse with a baking soda solution after vomiting and delay brushing for at least 30 minutes. Persistent vomiting raises the chance of enamel erosion and tooth fracture, so reach out early to prevent irreversible damage.

When to Call Your Dentist Right Now

Call if you notice new sensitivity to hot or cold temperatures, bleeding gums, persistent bad breath, loose teeth, tooth chips, or sudden changes in bite or tooth position. Those signs can mark enamel loss, gum disease, or an infection that needs prompt treatment. Your dentist can assess for: 

  • Enamel erosion

  • Gum recession

  • Dry mouth-related decay

  • Recommend targeted care

When to Talk With Your Doctor About Adjusting Treatment

If nausea, vomiting, or prolonged dry mouth interfere with eating or oral care, speak with your prescribing clinician. They can review dose, timing, or add anti-nausea therapies. If nutrient intake falls because you cannot eat, your doctor can check your calcium and vitamin D levels and advise on supplements or refer you to a dietitian.

How Dentists and Doctors Can Work Together for Safer Weight Loss

Tell both your dentist and your prescribing physician that you use a GLP-1 medication such as: 

  • Ozempic

  • Wegovy

  • Mounjaro

Your dentist can monitor for enamel erosion, cavity formation, gum disease, and changes in saliva. Your doctor can address nausea and vomiting and adjust the dose as needed. Communication enables each clinician to act early and prevent tooth loss or severe infections.

Practical Daily Checklist You Can Use Today

  • Brush your teeth twice daily for at least two minutes using a fluoride toothpaste.  

  • Floss once per day.  

  • Sip water throughout the day and chew sugar-free gum after meals to help maintain your oral health.  

  • Use an alcohol free saliva rinse if dryness persists.  

  • Avoid sugary and acidic snacks between meals.  

  • Rinse with a baking soda solution after vomiting and wait before brushing your teeth.  

  • Schedule dental visits for a checkup and cleaning every six months or sooner if advised.  

  • Notify both your dentist and prescribing doctor about new oral symptoms.

Quotes and Clinical Perspective You Can Trust

Ehsan Ali, MD, a Beverly Hills concierge doctor and board-certified in internal and geriatric medicine, linked oral problems associated with GLP-1 drugs to broader health risks and recommended hydration, saliva support, and a steady diet. He said that nutrients like calcium and vitamin D support oral health and advised avoiding skipping meals even when appetite falls. He also advised rinsing with water and baking soda after vomiting before brushing to neutralize stomach acid. Another clinician recommended avoiding alcohol, tobacco, and caffeine because they worsen dry mouth and reduce saliva flow.

Questions That Help Your Care

  • Are you experiencing chronic dry mouth, new sensitivity, or frequent vomiting? 

  • Have you had a dental checkup since starting your medication? 

Ask your dentist about professional fluoride options and ask your doctor about dose adjustments if side effects affect your mouth or ability to eat.

Related Reading

Can Ozempic Cause Muscle Pain
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Does Semaglutide Cause Bruising
Does Ozempic Cause Hiccups
Does Wegovy Cause Insomnia
Does Ozempic Cause Hair Loss
• Does Ozempic Cause Kidney Stones
• Does Ozempic Make You Tired
• Can Ozempic Cause Gallbladder Issues
• Can Ozempic Cause Muscle Pain

Download our GLP-1 app to Turn Your Weight Loss Journey into Your Favorite Game

MeAgain helps people who start Ozempic, Wegovy, or Mounjaro stay healthy while they lose weight. The app turns daily nutrition, hydration, fiber, protein, and movement into a game with an encouraging capybara guide. Hit targets, log milestones, and track progress with the Journey Card so you can capture memories of rapid change. Download MeAgain and make your weight loss routine feel like play.

Choosing Ozempic, Wegovy, Or Mounjaro: What Starting Treatment Looks Like

Which medication fits you? Ozempic and Wegovy are both semaglutide with different doses and labeled uses. Mounjaro uses tirzepatide, which can alter appetite and digestion in various ways. Expect nausea, slower gastric emptying, and appetite suppression in the early stages. Work with your prescribing clinician to determine the optimal dose and titrate as needed. Check labs and muscle markers as necessary.

Protect Muscle Mass While Losing Weight On GLP-1 Medications

Losing fat fast can also strip muscle if you do not prioritize protein and resistance training. Aim for approximately 1.2 to 2.0 grams of protein per kilogram of body weight at each meal, depending on your activity level and age. Add two to three resistance sessions a week, with progressive overload when you can tolerate it. Track your protein goals in MeAgain so you can consistently meet them as your appetite shifts.

Preventing Severe Constipation And GI Trouble On GLP-1 Treatment

Constipation and slow bowel movements are common when gastric motility changes. Increase your intake of soluble and insoluble fiber gradually, and chase meals with water. Stay active every day. Use osmotic laxatives or stool softeners only under a clinician's advice if lifestyle measures fail. Log your bowel patterns in the app to identify trends and share objective data with your healthcare professional, such as your clinician or pharmacist.

Oral Health And Ozempic: Does Ozempic Cause Tooth Decay?

Worried about cavities or enamel erosion while on GLP 1s? GLP-1 medications do not directly dissolve tooth enamel. Side effects can increase dental risk:

  • Dry mouth or xerostomia lowers saliva, which is your mouth’s natural defense against cavities and acid. 

  • Increased reflux or occasional vomiting raises exposure to stomach acid and can strip enamel. 

  • Sugar cravings, sipping sweet drinks, and poor brushing when appetite changes also increase cavity and gum disease risk, like gingivitis and periodontitis. 

See a dentist soon after starting therapy and schedule more frequent cleanings if you develop dry mouth, bad breath, or signs of erosion. Daily fluoride toothpaste, topical fluoride when recommended, gentle brushing after reflux episodes, and chewing sugar-free gum to stimulate saliva help prevent decay.

How Meagain Helps Reduce Dental Risks While You Lose Weight

MeAgain nudges you to increase water intake, fiber, and eat meals on time, so you don't rely on sugary snacks between meals. The capybara reminds you to brush and floss, and Journey Cards can store photos of dental visits and notes from your dentist. Logging symptoms such as dry mouth, acid reflux, or tooth sensitivity creates a shareable report for your dentist and prescriber. These small habits lower the risk for cavities, halitosis, and enamel erosion over weeks and months.

Integrating Meagain With Your Medical And Dental Team

Share tracked trends from MeAgain with your clinician and dentist before appointments. Objective data on: 

  • Hydration

  • Stool frequency

  • Protein intake

  • Reflux episodes 

Inform decisions about: 

  • Laxatives

  • Dose adjustments

  • Dental interventions

Ask your provider about saliva substitutes, topical fluoride, or referral to a dental specialist if you show persistent enamel loss or gum inflammation.

Daily Habits The App Turns Into Wins

Protein targets prevent muscle loss. Fiber goals reduce constipation. Water check-ins keep saliva flowing. Short exercise sessions protect lean mass and digestion. The app provides reminders, streaks, and rewards, enabling you to consistently repeat healthy actions without needing to think about them.

When To Contact Your Provider Or Dentist

Call your clinician for: 

  • Severe nausea

  • Unmanageable constipation

  • Rapid muscle weakness

Contact a dentist for: 

  • Tooth sensitivity

  • New cavities

  • Chipped enamel

  • Persistent dry mouth

If you experience severe reflux or repeated vomiting, get medical attention and ask about strategies to protect your teeth.

Journey Card And Capturing Milestones While Staying Safe

Use the Journey Card to record weigh-ins, strength gains, dental check-ups, and changes in symptoms. Take photographs of scars, body changes, or a healed mouth ulcer to keep precise records for both clinicians and yourself. Capturing milestones helps maintain momentum and provides your care team with concrete data to refine therapy.

Related Reading

• Does Mounjaro Affect Fertility
• Zepbound Side Effects: Muscle Pain
• Tirzepatide Side Effects Long-term
• Wegovy Mental Side Effects
• How Much Water Should I Drink on Semaglutide
• What to Eat While on Wegovy
• Does Mounjaro Lower Cholesterol
• Does Ozempic Cause Eye Problems
• How Long Do Side Effects of Wegovy Last
• How to Make Wegovy Work Better
• What to Eat on Mounjaro